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Resources Studies

Studies

Many studies have examined the effectiveness and safety of using scalp cooling caps. The examples we have presented are only part of the available documentation. We also encourage you to carry out your own research on credible and recognized medical platforms.

COOLHAIR: a prospective randomized trial to investigate the efficacy and tolerability of scalp cooling in patients undergoing (neo)adjuvant chemotherapy for early breast cancer

Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients: The HOPE Study

Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy

Scalp Cooling Alopecia Prevention Trial (SCALP) for patients with early-stage breast cancer early.

Scalp Cooling in Preventing Persistent Chemiotherapy-Induced Alopecia : A Randomized Controlled Trial. - June 2024

Manual scalp cooling in early-stage breast cancer case report: Value of caretaker training and patient experience to optimize efficacy and patient selection.

Retrospective evaluation of Penguin Cold Caps for chemotherapy-induced alopecia. Scalp cooling is an increasingly recognized non-pharmacologic approach to minimize chemotherapy-induced alopecia (CIA). This study was a single-institution review of outcomes from manual cold capping.

Efficacy of Scalp Cooling in Preventing Chemotherapy-Induced Alopecia in Breast Cancer Patients Receiving Adjuvant Docetaxel and Cyclophosphamide Chemotherapy

Scalp Hypothermia (Penguin Cold Caps) in Preventing Alopecia in Cancer Patients.

Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis.

Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy.

Real-World Use of Scalp Cooling to Reduce Chemotherapy-Related Hair Loss.

Scalp cooling to prevent chemotherapy-induced alopecia. Scalp cooling does not appear to increase the risk of cutaneous scalp metastases in early-stage breast cancer patients, nor does it appear to compromise cancer outcome.

Safety and efficacy of scalp cooling system in preventing chemotherapy induced alopecia - A single center prospective study

Efficacy of scalp cooling for prevention of chemotherapy induced alopecia: a systematic review and meta-analysis. The current meta-analysis suggests that in female patients with breast cancer, the use of scalp cooling, compared to no scalp cooling, reduces the risk of significant hair loss.

​Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer. Cooling system was associated with a lower risk of hair loss among women receiving non–anthracycline-based chemotherapy for early-stage breast cancer.

Efficacy of Scalp Cooling in Preventing and Recovering From Chemotherapy-Induced Alopecia in Breast Cancer Patients Scalp cooling resulted in faster recovery of hair volume after chemotherapy.

​Scalp cooling to prevent chemotherapy-induced alopecia - Scalp cooling is an approved and generally well-tolerated option to prevent CIA and can minimize the burden of cancer treatment and potential impairments in patients’ health-related quality of life and psychosocial well-being.

Scalp Cooling: The Prevention of Chemotherapy-Induced Alopecia - Scalp metastases: ​the incidence is so low in women with breast cancer that scalp cooling can be provided without the risk of this rare occurrence ​